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BDNF/TRKB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer
Parotid gland cancer (PGC) is a rare malignancy and its molecular characteristics remain poorly understood, which has precluded the development of effective drug therapies. Given the poor prognosis of many human cancers in which tropomyosin receptor kinase B (TRKB) is highly expressed, we investigat...
Autores principales: | Moriwaki, Kazumasa, Wada, Masaki, Kuwabara, Hiroko, Ayani, Yusuke, Terada, Tetsuya, Higashino, Masaaki, Kawata, Ryo, Asahi, Michio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584965/ https://www.ncbi.nlm.nih.gov/pubmed/36266462 http://dx.doi.org/10.1038/s41598-022-22377-9 |
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