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BDNF/TRKB axis provokes EMT progression to induce cell aggressiveness via crosstalk with cancer-associated fibroblasts in human parotid gland cancer

Parotid gland cancer (PGC) is a rare malignancy and its molecular characteristics remain poorly understood, which has precluded the development of effective drug therapies. Given the poor prognosis of many human cancers in which tropomyosin receptor kinase B (TRKB) is highly expressed, we investigat...

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Detalles Bibliográficos
Autores principales: Moriwaki, Kazumasa, Wada, Masaki, Kuwabara, Hiroko, Ayani, Yusuke, Terada, Tetsuya, Higashino, Masaaki, Kawata, Ryo, Asahi, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584965/
https://www.ncbi.nlm.nih.gov/pubmed/36266462
http://dx.doi.org/10.1038/s41598-022-22377-9

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