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Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2

Intestinal stem cells (ISCs) are responsible for intestinal tissue homeostasis and are important for the regeneration of the damaged intestinal epithelia. Through the establishment of ionizing radiation (IR) induced intestinal injury model, we found that a TLR2 agonist, Zymosan-A, promoted the regen...

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Detalles Bibliográficos
Autores principales: Du, Jicong, Fang, Lan, Zhao, Jianpeng, Yu, Yike, Feng, Zhenlan, Wang, Yuedong, Cheng, Ying, Li, Bailong, Gao, Fu, Liu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585075/
https://www.ncbi.nlm.nih.gov/pubmed/36266266
http://dx.doi.org/10.1038/s41419-022-05301-x