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The roles of two extracellular loops in proton sensing and permeation in human Otop1 proton channel

Otopetrin (Otop) proteins were recently found to function as proton channels, with Otop1 revealed to be the sour taste receptor in mammals. Otop proteins contain twelve transmembrane segments (S1-S12) which are divided into structurally similar N and C domains. The mechanisms by which Otop channels...

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Detalles Bibliográficos
Autores principales:	Li, Bin, Wang, Yan, Castro, Alexis, Ng, Courtney, Wang, Zhifei, Chaudhry, Haroon, Agbaje, Zainab, Ulloa, Gabriella A., Yu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585144/ https://www.ncbi.nlm.nih.gov/pubmed/36266567 http://dx.doi.org/10.1038/s42003-022-04085-2

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