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Effects of metformin on Sonic hedgehog subgroup medulloblastoma progression: In vitro and in vivo studies

Metformin is a first-line drug for type 2 diabetes, and its anticancer effects have also been widely studied in recent years. The Sonic hedgehog (Shh) signaling pathway is involved in the initiation and progression of medulloblastoma. In order to develop a new treatment strategy for medulloblastoma...

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Detalles Bibliográficos
Autores principales: Fang, Huangyi, Wang, Lingfei, Yu, Lisheng, Shen, Fang, Yang, Zelin, Yang, Yue, Li, Shize, Dai, Haipeng, Tan, Feng, Lin, Jian, Sheng, Hansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585190/
https://www.ncbi.nlm.nih.gov/pubmed/36278239
http://dx.doi.org/10.3389/fphar.2022.928853