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The Association Between Living Area in Childhood and Respiratory Disease Mortality in Adulthood

Objective: No studies have examined the association between characteristics of urban areas and future respiratory disease mortality. We examined whether the type of living area during childhood was associated with all-cause and respiratory disease mortality in adulthood. Methods: A total of 81,413 J...

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Detalles Bibliográficos
Autores principales: Iwasaki, Ayumu, Teramoto, Masayuki, Muraki, Isao, Shirai, Kokoro, Tamakoshi, Akiko, Iso, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585191/
https://www.ncbi.nlm.nih.gov/pubmed/36275433
http://dx.doi.org/10.3389/ijph.2022.1604778
Descripción
Sumario:Objective: No studies have examined the association between characteristics of urban areas and future respiratory disease mortality. We examined whether the type of living area during childhood was associated with all-cause and respiratory disease mortality in adulthood. Methods: A total of 81,413 Japanese participants aged 40–79 years old completed a lifestyle questionnaire including the type of childhood living areas. The Cox proportional hazards regression model was used to calculate the multivariable hazard ratios (HRs) with 95% confidence intervals (CIs) of all-cause and respiratory disease mortality. Results: Living in large city areas in childhood was associated with a higher risk of all-cause mortality [HR = 1.05 (95% CI, 1.01–1.10)], but not with respiratory disease mortality [HR = 1.04 (95% CI, 0.92–1.18)] compared to rural and remote areas. The excess risk of all-cause and respiratory disease mortality was primarily found in industrial areas among men; the respective multivariable HRs were 1.28 (95% CI, 1.00–1.64) and 1.90 (95% CI: 1.10–3.29). Conclusion: Eliminating childhood health hazards associated with living in industrial areas suggested to reduce the risk of mortality from respiratory diseases in adulthood.