Multiple Sclerosis CSF Is Enriched With Follicular T Cells Displaying a Th1/Eomes Signature

BACKGROUND AND OBJECTIVES: Tertiary lymphoid structures and aggregates are reported in the meninges of patients with multiple sclerosis (MS), especially at the progressive stage, and are strongly associated with cortical lesions and disability. Besides B cells, these structures comprise follicular h...

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Detalles Bibliográficos
Autores principales: Morille, Jérémy, Mandon, Marion, Rodriguez, Stéphane, Roulois, David, Leonard, Simon, Garcia, Alexandra, Wiertlewski, Sandrine, Le Page, Emmanuelle, Berthelot, Laureline, Nicot, Arnaud, Mathé, Camille, Lejeune, Flora, Tarte, Karin, Delaloy, Céline, Amé, Patricia, Laplaud, David, Michel, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585484/
https://www.ncbi.nlm.nih.gov/pubmed/36266053
http://dx.doi.org/10.1212/NXI.0000000000200033

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