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Investigation of Acid–Base Catalysis in Halimadienyl Diphosphate Synthase Involved in Mycobacterium tuberculosis Virulence
[Image: see text] The devastating human pathogenMycobacterium tuberculosis (Mtb) is able to parasitize phagosomal compartments within alveolar macrophage cells due, in part, to the activity of its cell-surface lipids. Prominent among these is 1-tuberculosinyl-adenosine (1-TbAd), a derivative of the...
Autores principales: | Lemke, Cody, Roach, Kristin, Ortega, Teresa, Tantillo, Dean J., Siegel, Justin B., Peters, Reuben J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585517/ https://www.ncbi.nlm.nih.gov/pubmed/36281298 http://dx.doi.org/10.1021/acsbiomedchemau.2c00023 |
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