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Quantification of Engagement of Microtubules by Small Molecules in Living Cells by Flow Cytometry
[Image: see text] Drugs such as paclitaxel (Taxol) that bind microtubules are widely used for the treatment of cancer. Measurements of the affinity and selectivity of these compounds for their targets are largely based on studies of purified proteins, and only a few quantitative methods for the anal...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585582/ https://www.ncbi.nlm.nih.gov/pubmed/36281300 http://dx.doi.org/10.1021/acsbiomedchemau.2c00031 |