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Targeting the high affinity receptor, FcγRI, in autoimmune disease, neuropathy, and cancer
The Fc gamma receptor I (FcγRI or CD64) is the only human Fc receptor with a high affinity for monomeric IgG. It plays a crucial role in immunity, as it mediates cellular effector functions of antibodies including phagocytosis, antigen presentation, and cytokine production. FcγRI is constitutively s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585681/ https://www.ncbi.nlm.nih.gov/pubmed/36284837 http://dx.doi.org/10.1093/immadv/ltac011 |