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Targeting the high affinity receptor, FcγRI, in autoimmune disease, neuropathy, and cancer

The Fc gamma receptor I (FcγRI or CD64) is the only human Fc receptor with a high affinity for monomeric IgG. It plays a crucial role in immunity, as it mediates cellular effector functions of antibodies including phagocytosis, antigen presentation, and cytokine production. FcγRI is constitutively s...

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Detalles Bibliográficos
Autores principales: Holtrop, Tosca, Budding, Kevin, Brandsma, Arianne M, Leusen, Jeanette H W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585681/
https://www.ncbi.nlm.nih.gov/pubmed/36284837
http://dx.doi.org/10.1093/immadv/ltac011