DNAM1 and TIGIT balance the T cell response, with low T cell TIGIT expression corresponding to inflammation in psoriatic disease

OBJECTIVES: Signals at the contact site of antigen-presenting cells (APCs) and T cells help orchestrate the adaptive immune response. CD155 on APCs can interact with the stimulatory receptor DNAM1 or inhibitory receptor TIGIT on T cells. The CD155/DNAM1/TIGIT axis is under extensive investigation as...

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Detalles Bibliográficos
Autores principales: Jacobs, Marleen E, Pouw, Juliëtte N, Olde Nordkamp, Michel A, Radstake, Timothy R D J, Leijten, Emmerik F A, Boes, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585685/
https://www.ncbi.nlm.nih.gov/pubmed/36284900
http://dx.doi.org/10.1093/immadv/ltaa004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585685/
https://www.ncbi.nlm.nih.gov/pubmed/36284900
http://dx.doi.org/10.1093/immadv/ltaa004

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