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Identification of a window of androgen sensitivity for somatic cell function in human fetal testis cultured ex vivo

BACKGROUND: Reduced androgen action during early fetal development has been suggested as the origin of reproductive disorders comprised within the testicular dysgenesis syndrome (TDS). This hypothesis has been supported by studies in rats demonstrating that normal male development and adult reproduc...

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Detalles Bibliográficos
Autores principales: Lundgaard Riis, Malene, Matilionyte, Gabriele, Nielsen, John E., Melau, Cecilie, Greenald, David, Juul Hare, Kristine, Langhoff Thuesen, Lea, Dreisler, Eva, Aaboe, Kasper, Brenøe, Pia Tutein, Andersson, Anna-Maria, Albrethsen, Jakob, Frederiksen, Hanne, Rajpert-De Meyts, Ewa, Juul, Anders, Mitchell, Rod T., Jørgensen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585726/
https://www.ncbi.nlm.nih.gov/pubmed/36266662
http://dx.doi.org/10.1186/s12916-022-02602-y