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Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
BACKGROUND: Microglia are the resident immune cells found in our brain. They have a critical role in brain maintenance. Microglia constantly scavenge various waste materials in the brain including damaged or apoptotic neurons and Aβ. Through phagocytosis of Aβ, microglia prevent the accumulation of...
Autores principales: | Jo, Kyung Won, Lee, Dohyun, Cha, Dong Gon, Oh, Eunji, Choi, Yoon Ha, Kim, Somi, Park, Eun Seo, Kim, Jong Kyoung, Kim, Kyong-Tai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585741/ https://www.ncbi.nlm.nih.gov/pubmed/36271414 http://dx.doi.org/10.1186/s13195-022-01096-3 |
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