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A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures

BACKGROUND: Endplate fractures is an important factor affecting the curative effect of percutaneous kyphoplasty for spinal fracture. The purpose of this study is to investigate the effect of sealing endplate fracture with bone cement on minimally invasive treatment of spinal fracture. METHODS: A tot...

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Autores principales: Zhao, Zhijian, Deng, Lei, Hua, Xi, Liu, Haojun, Zhang, Hao, Jia, Xuejun, Wei, Rushuai, Liu, Mingming, Lv, Nanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585934/
https://www.ncbi.nlm.nih.gov/pubmed/36277290
http://dx.doi.org/10.3389/fsurg.2022.999406
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author Zhao, Zhijian
Deng, Lei
Hua, Xi
Liu, Haojun
Zhang, Hao
Jia, Xuejun
Wei, Rushuai
Liu, Mingming
Lv, Nanning
author_facet Zhao, Zhijian
Deng, Lei
Hua, Xi
Liu, Haojun
Zhang, Hao
Jia, Xuejun
Wei, Rushuai
Liu, Mingming
Lv, Nanning
author_sort Zhao, Zhijian
collection PubMed
description BACKGROUND: Endplate fractures is an important factor affecting the curative effect of percutaneous kyphoplasty for spinal fracture. The purpose of this study is to investigate the effect of sealing endplate fracture with bone cement on minimally invasive treatment of spinal fracture. METHODS: A total of 98 patients with osteoporotic vertebral fractures combined with endplate fractures treated with bone cement surgery in our hospital were retrospectively analyzed. They were grouped according to whether bone cement was involved in the endplate fractures. Group A: bone cement was not only distributed in the fractured vertebral body, but also dispersed into the endplate fractures. Group B: bone cement was confined to the fractured vertebra but did not diffuse into the cracks of the endplate. The basic information, imaging changes of the fractured vertebral body, VAS score, ODI score, bone cement distribution and postoperative complications of the two groups were analyzed and compared. RESULTS: The height of the injured vertebra and the kyphotic Cobb angle in the two groups were significantly improved after surgery, but the anterior height of the vertebra in group B was lower than that in group A and the kyphotic Cobb angle was higher than that in group A at the last follow-up (P < 0.05). VAS score and ODI score in 2 groups were significantly improved after operation (P < 0.05), but the VAS score and ODI score in group A were lower than those in group B at the last follow-up (P < 0.05). The incidence of bone cement leakage and adjacent vertebral fracture in group A was higher than that in group B (P < 0.05). CONCLUSION: Diffusion of bone cement into the cracks of the endplate may also restore and maintain the height of the injured vertebra, relieve pain and restore lumbar function. However, diffusion of bone cement into the cracks of the endplate can increase the incidence of cement leakage and adjacent vertebral fractures.
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spelling pubmed-95859342022-10-22 A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures Zhao, Zhijian Deng, Lei Hua, Xi Liu, Haojun Zhang, Hao Jia, Xuejun Wei, Rushuai Liu, Mingming Lv, Nanning Front Surg Surgery BACKGROUND: Endplate fractures is an important factor affecting the curative effect of percutaneous kyphoplasty for spinal fracture. The purpose of this study is to investigate the effect of sealing endplate fracture with bone cement on minimally invasive treatment of spinal fracture. METHODS: A total of 98 patients with osteoporotic vertebral fractures combined with endplate fractures treated with bone cement surgery in our hospital were retrospectively analyzed. They were grouped according to whether bone cement was involved in the endplate fractures. Group A: bone cement was not only distributed in the fractured vertebral body, but also dispersed into the endplate fractures. Group B: bone cement was confined to the fractured vertebra but did not diffuse into the cracks of the endplate. The basic information, imaging changes of the fractured vertebral body, VAS score, ODI score, bone cement distribution and postoperative complications of the two groups were analyzed and compared. RESULTS: The height of the injured vertebra and the kyphotic Cobb angle in the two groups were significantly improved after surgery, but the anterior height of the vertebra in group B was lower than that in group A and the kyphotic Cobb angle was higher than that in group A at the last follow-up (P < 0.05). VAS score and ODI score in 2 groups were significantly improved after operation (P < 0.05), but the VAS score and ODI score in group A were lower than those in group B at the last follow-up (P < 0.05). The incidence of bone cement leakage and adjacent vertebral fracture in group A was higher than that in group B (P < 0.05). CONCLUSION: Diffusion of bone cement into the cracks of the endplate may also restore and maintain the height of the injured vertebra, relieve pain and restore lumbar function. However, diffusion of bone cement into the cracks of the endplate can increase the incidence of cement leakage and adjacent vertebral fractures. Frontiers Media S.A. 2022-10-06 /pmc/articles/PMC9585934/ /pubmed/36277290 http://dx.doi.org/10.3389/fsurg.2022.999406 Text en © 2022 Zhao, Deng, Hua, Liu, Zhang, Jia, Wei, Liu and Lv. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Zhao, Zhijian
Deng, Lei
Hua, Xi
Liu, Haojun
Zhang, Hao
Jia, Xuejun
Wei, Rushuai
Liu, Mingming
Lv, Nanning
A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title_full A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title_fullStr A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title_full_unstemmed A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title_short A retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
title_sort retrospective study on the efficacy and safety of bone cement in the treatment of endplate fractures
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585934/
https://www.ncbi.nlm.nih.gov/pubmed/36277290
http://dx.doi.org/10.3389/fsurg.2022.999406
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