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Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)

A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermati...

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Autores principales: YOSHIDA, Kio, CHAMBERS, James K, UCHIDA, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586031/
https://www.ncbi.nlm.nih.gov/pubmed/36058878
http://dx.doi.org/10.1292/jvms.22-0317
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author YOSHIDA, Kio
CHAMBERS, James K
UCHIDA, Kazuyuki
author_facet YOSHIDA, Kio
CHAMBERS, James K
UCHIDA, Kazuyuki
author_sort YOSHIDA, Kio
collection PubMed
description A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermatitis, and endocarditis characterized by severe neutrophilic infiltration were observed. Gram-positive cocci arranged in pairs or chains were present in these inflammatory lesions. Streptococcus agalactiae gene was detected in the skin, heart, and brain tissues by PCR and sequence analysis. These findings may indicate that S. agalactiae primarily infected the skin and then caused septicemia resulting in endocarditis and meningo-ventriculitis. The present case suggests that S. agalactiae infection can cause severe meningo-ventriculitis in two-toed sloth without any specific clinical signs.
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spelling pubmed-95860312022-11-07 Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus) YOSHIDA, Kio CHAMBERS, James K UCHIDA, Kazuyuki J Vet Med Sci Wildlife Science A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermatitis, and endocarditis characterized by severe neutrophilic infiltration were observed. Gram-positive cocci arranged in pairs or chains were present in these inflammatory lesions. Streptococcus agalactiae gene was detected in the skin, heart, and brain tissues by PCR and sequence analysis. These findings may indicate that S. agalactiae primarily infected the skin and then caused septicemia resulting in endocarditis and meningo-ventriculitis. The present case suggests that S. agalactiae infection can cause severe meningo-ventriculitis in two-toed sloth without any specific clinical signs. The Japanese Society of Veterinary Science 2022-09-02 2022-10 /pmc/articles/PMC9586031/ /pubmed/36058878 http://dx.doi.org/10.1292/jvms.22-0317 Text en ©2022 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Wildlife Science
YOSHIDA, Kio
CHAMBERS, James K
UCHIDA, Kazuyuki
Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title_full Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title_fullStr Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title_full_unstemmed Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title_short Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
title_sort systemic streptococcus agalactiae infection with meningo-ventriculitis in a linnaeus’s two-toed sloth (choloepus didactylus)
topic Wildlife Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586031/
https://www.ncbi.nlm.nih.gov/pubmed/36058878
http://dx.doi.org/10.1292/jvms.22-0317
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