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Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus)
A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586031/ https://www.ncbi.nlm.nih.gov/pubmed/36058878 http://dx.doi.org/10.1292/jvms.22-0317 |
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author | YOSHIDA, Kio CHAMBERS, James K UCHIDA, Kazuyuki |
author_facet | YOSHIDA, Kio CHAMBERS, James K UCHIDA, Kazuyuki |
author_sort | YOSHIDA, Kio |
collection | PubMed |
description | A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermatitis, and endocarditis characterized by severe neutrophilic infiltration were observed. Gram-positive cocci arranged in pairs or chains were present in these inflammatory lesions. Streptococcus agalactiae gene was detected in the skin, heart, and brain tissues by PCR and sequence analysis. These findings may indicate that S. agalactiae primarily infected the skin and then caused septicemia resulting in endocarditis and meningo-ventriculitis. The present case suggests that S. agalactiae infection can cause severe meningo-ventriculitis in two-toed sloth without any specific clinical signs. |
format | Online Article Text |
id | pubmed-9586031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-95860312022-11-07 Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus) YOSHIDA, Kio CHAMBERS, James K UCHIDA, Kazuyuki J Vet Med Sci Wildlife Science A captive male Linnaeus’s two-toed sloth died without any obvious clinical signs. At necropsy, multifocal ulceration at the lumbar and perianal skin, mitral valve vegetation, and multifocal hemorrhage in the leptomeninges were observed. Histopathologically, suppurative meningo-ventriculitis, dermatitis, and endocarditis characterized by severe neutrophilic infiltration were observed. Gram-positive cocci arranged in pairs or chains were present in these inflammatory lesions. Streptococcus agalactiae gene was detected in the skin, heart, and brain tissues by PCR and sequence analysis. These findings may indicate that S. agalactiae primarily infected the skin and then caused septicemia resulting in endocarditis and meningo-ventriculitis. The present case suggests that S. agalactiae infection can cause severe meningo-ventriculitis in two-toed sloth without any specific clinical signs. The Japanese Society of Veterinary Science 2022-09-02 2022-10 /pmc/articles/PMC9586031/ /pubmed/36058878 http://dx.doi.org/10.1292/jvms.22-0317 Text en ©2022 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Wildlife Science YOSHIDA, Kio CHAMBERS, James K UCHIDA, Kazuyuki Systemic Streptococcus agalactiae infection with meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus didactylus) |
title | Systemic Streptococcus agalactiae infection with
meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus
didactylus) |
title_full | Systemic Streptococcus agalactiae infection with
meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus
didactylus) |
title_fullStr | Systemic Streptococcus agalactiae infection with
meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus
didactylus) |
title_full_unstemmed | Systemic Streptococcus agalactiae infection with
meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus
didactylus) |
title_short | Systemic Streptococcus agalactiae infection with
meningo-ventriculitis in a Linnaeus’s two-toed sloth (Choloepus
didactylus) |
title_sort | systemic streptococcus agalactiae infection with
meningo-ventriculitis in a linnaeus’s two-toed sloth (choloepus
didactylus) |
topic | Wildlife Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586031/ https://www.ncbi.nlm.nih.gov/pubmed/36058878 http://dx.doi.org/10.1292/jvms.22-0317 |
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