Clinical associations and genetic interactions of oncogenic BRAF alleles

BRAF is a serine/threonine-specific protein kinase that regulates the MAPK/ERK signaling pathway, and mutations in the BRAF gene are considered oncogenic drivers in diverse types of cancer. Based on the signaling mechanism, oncogenic BRAF mutations can be assigned to three different classes: class 1...

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Detalles Bibliográficos
Autor principal: Wagner, Sebastian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586110/
https://www.ncbi.nlm.nih.gov/pubmed/36275468
http://dx.doi.org/10.7717/peerj.14126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586110/
https://www.ncbi.nlm.nih.gov/pubmed/36275468
http://dx.doi.org/10.7717/peerj.14126

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