Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment

The FcγRII (CD32) ligands are IgFc fragments and pentraxins. The existence of additional ligands is unknown. We engineered T cells with human chimeric receptors resulting from the fusion between CD32 extracellular portion and transmembrane CD8α linked to CD28/ζ chain intracellular moiety (CD32-CR)....

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Detalles Bibliográficos
Autores principales: Sconocchia, Giuseppe, Lanzilli, Giulia, Cesarini, Valeriana, Silvestris, Domenico A, Rezvani, Katayoun, Arriga, Roberto, Caratelli, Sara, Chen, Ken, Dou, Jinzhuang, Cenciarelli, Carlo, Toietta, Gabriele, Baldari, Silvia, Sconocchia, Tommaso, De Paolis, Francesca, Aureli, Anna, Iezzi, Giandomenica, Irno Consalvo, Maria, Buccisano, Francesco, del Principe, Maria I, Maurillo, Luca, Venditti, Adriano, Ottaviani, Alessio, Spagnoli, Giulio C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586128/
https://www.ncbi.nlm.nih.gov/pubmed/36241426
http://dx.doi.org/10.26508/lsa.202201590

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