Cargando…

Identification of minimum essential therapeutic mixtures from cannabis plant extracts by screening in cell and animal models of Parkinson’s disease

Medicinal cannabis has shown promise for the symptomatic treatment of Parkinson’s disease (PD), but patient exposure to whole plant mixtures may be undesirable due to concerns around safety, consistency, regulatory issues, and psychoactivity. Identification of a subset of components responsible for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morash, Michael G., Nixon, Jessica, Shimoda, Lori M. N., Turner, Helen, Stokes, Alexander J., Small-Howard, Andrea L., Ellis, Lee D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586206/ https://www.ncbi.nlm.nih.gov/pubmed/36278152 http://dx.doi.org/10.3389/fphar.2022.907579

Ejemplares similares

Pharmacokinetics of Cannabis and Its Derivatives in Animals and Humans During Pregnancy and Breastfeeding
por: Monfort, Anaëlle, et al.
Publicado: (2022)

Cannabis Chemovar Nomenclature Misrepresents Chemical and Genetic Diversity; Survey of Variations in Chemical Profiles and Genetic Markers in Nevada Medical Cannabis Samples
por: Reimann-Philipp, Ulrich, et al.
Publicado: (2020)

Metabolomic Fingerprint of Behavioral Changes in Response to Full-Spectrum Cannabis Extracts
por: Maayah, Zaid H., et al.
Publicado: (2022)

Essential Oils as Multicomponent Mixtures and Their Potential for Human Health and Well-Being
por: Bunse, Marek, et al.
Publicado: (2022)

Assessing the bioactivity of cannabis extracts in larval zebrafish
por: Nixon, Jessica, et al.
Publicado: (2021)

Standardized Cannabis Smoke Extract Induces Inflammation in Human Lung Fibroblasts
por: Aloufi, Noof, et al.
Publicado: (2022)

Preparation and Distribution of Cannabis and Cannabis-Derived Dosage Formulations for Investigational and Therapeutic Use in the United States
por: Thomas, Brian F., et al.
Publicado: (2016)

Evaluation of two different Cannabis sativa L. extracts as antioxidant and neuroprotective agents
por: Cásedas, Guillermo, et al.
Publicado: (2022)

Treatment With Medicinal Mushroom Extract Mixture Inhibits Translation and Reprograms Metabolism in Advanced Colorectal Cancer Animal Model as Evidenced by Tandem Mass Tags Proteomics Analysis
por: Jakopovic, Boris, et al.
Publicado: (2020)

Impact of Cannabis, Cannabinoids, and Endocannabinoids in the Lungs
por: Turcotte, Caroline, et al.
Publicado: (2016)

Can Prescribed Cannabinoids Substitute Cannabis?
por: Batalla, A.
Publicado: (2022)

Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules
por: Zagzoog, Ayat, et al.
Publicado: (2022)

Sub-Minimum Inhibitory Concentrations of Rhubarb Water Extracts Inhibit Streptococcus suis Biofilm Formation
por: Ding, Wen-Ya, et al.
Publicado: (2017)

Cannabis Contaminants Limit Pharmacological Use of Cannabidiol
por: Montoya, Zackary, et al.
Publicado: (2020)

Medicinal Cannabis and Central Nervous System Disorders
por: Ortiz, Yuma T., et al.
Publicado: (2022)

Differentiating Cannabis Products: Drugs, Food, and Supplements
por: Salehi, Arash, et al.
Publicado: (2022)

Cannabis: a multifaceted plant with endless potentials
por: Fordjour, Eric, et al.
Publicado: (2023)

Neuroprotective Studies on Polygonum hydropiper L. Essential Oils Using Transgenic Animal Models
por: Tong, Xin, et al.
Publicado: (2021)

Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity
por: Samarut, Éric, et al.
Publicado: (2019)

Evaluating the Effects of Gamma-Irradiation for Decontamination of Medicinal Cannabis
por: Hazekamp, Arno
Publicado: (2016)

Risks of harm with cannabinoids, cannabis, and cannabis-based medicine for pain management relevant to patients receiving pain treatment: protocol for an overview of systematic reviews
por: Gilron, Ian, et al.
Publicado: (2019)

Cannabis, cannabinoids, and health
por: Lafaye, Genevieve, et al.
Publicado: (2017)

Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain
por: Gazarov, Emely A., et al.
Publicado: (2023)

An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse
por: Pagano, Ester, et al.
Publicado: (2016)

Too young for Cannabis? Choice of minimum legal age for legalized non-medical Cannabis in Canada
por: Nguyen, Hai V., et al.
Publicado: (2020)

Changes in Youth Cannabis Use After an Increase in Cannabis Minimum Legal Age in Quebec, Canada
por: Nguyen, Hai V., et al.
Publicado: (2022)

DA-9805, a Herbal Mixture, Restores Motor Manifestations in 6-Hydroxydopamine-induced Parkinson’s Disease Mouse Model by Regulating Striatal Dopamine and Acetylcholine Levels
por: Huh, Eugene, et al.
Publicado: (2022)

Current Therapeutic Cannabis Controversies and Clinical Trial Design Issues
por: Russo, Ethan B.
Publicado: (2016)

Patient-Reported Symptom Relief Following Medical Cannabis Consumption
por: Stith, Sarah S., et al.
Publicado: (2018)

Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective
por: Archie, Sabrina Rahman, et al.
Publicado: (2019)

The evolving culture of medical cannabis in Canada for the management of chronic pain
por: Clarke, H., et al.
Publicado: (2023)

Suitability of botanical extracts as components of complex mixtures used in herbal tea infusions—challenges and opportunities
por: Brendler, T., et al.
Publicado: (2022)

Suppression of Cisplatin-Induced Vomiting by Cannabis sativa in Pigeons: Neurochemical Evidences
por: Ullah, Ihsan, et al.
Publicado: (2018)

The Association of Unfavorable Traffic Events and Cannabis Usage: A Meta-Analysis
por: Hostiuc, Sorin, et al.
Publicado: (2018)

Cannabis for Neuropathic Pain in Multiple Sclerosis—High Expectations, Poor Data
por: Rudroff, Thorsten
Publicado: (2019)

Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action
por: Anil, Seegehalli M., et al.
Publicado: (2022)

Potency and Therapeutic THC and CBD Ratios: U.S. Cannabis Markets Overshoot
por: Pennypacker, Sarah D., et al.
Publicado: (2022)

Understanding feeling “high” and its role in medical cannabis patient outcomes
por: Stith, Sarah S., et al.
Publicado: (2023)

Medicinal cannabis for psychiatry-related conditions: an overview of current Australian prescribing
por: Cairns, Elizabeth A., et al.
Publicado: (2023)

Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease
por: Chen, Leilei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_44o25qi969h1ud4fc7leoouqdb