Challenges for the development of a universal vaccine against leptospirosis revealed by the evaluation of 22 vaccine candidates

Leptospirosis is a neglected disease of man and animals that affects nearly half a million people annually and causes considerable economic losses. Current human vaccines are inactivated whole-cell preparations (bacterins) of Leptospira spp. that provide strong homologous protection yet fail to indu...

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Detalles Bibliográficos
Autores principales: Maia, Mara A. C., Bettin, Everton B., Barbosa, Liana N., de Oliveira, Natasha R., Bunde, Tiffany T., Pedra, Ana Carolina K., Rosa, Guilherme A., da Rosa, Elias E. B., Seixas Neto, Amilton C. P., Grassmann, André A., McFadden, Johnjoe, Dellagostin, Odir A., McBride, Alan J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586249/
https://www.ncbi.nlm.nih.gov/pubmed/36275031
http://dx.doi.org/10.3389/fcimb.2022.940966

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