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Inducible general knockout of Runx3 profoundly reduces pulmonary cytotoxic CD8(+) T cells with minimal effect on outcomes in mice following influenza infection

Respiratory viruses pose a continuing and substantive threat to human health globally. Host innate and adaptive immune responses are the critical antiviral defense mechanisms to control viral replication and spread. The present study is designed to determine the role of transcription factor Runx3 in...

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Detalles Bibliográficos
Autores principales:	Hao, Qin, Kundu, Suman, Shetty, Sreerama, Tucker, Torry A., Idell, Steven, Tang, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586250/ https://www.ncbi.nlm.nih.gov/pubmed/36275778 http://dx.doi.org/10.3389/fimmu.2022.1011922

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