5-methylcytosine (m(5)C) RNA modification controls the innate immune response to virus infection by regulating type I interferons

5-methylcytosine (m(5)C) is one of the most prevalent modifications of RNA, playing important roles in RNA metabolism, nuclear export, and translation. However, the potential role of RNA m(5)C methylation in innate immunity remains elusive. Here, we show that depletion of NSUN2, an m(5)C methyltrans...

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Detalles Bibliográficos
Autores principales: Zhang, Yuexiu, Zhang, Li-Sheng, Dai, Qing, Chen, Phylip, Lu, Mijia, Kairis, Elizabeth L., Murugaiah, Valarmathy, Xu, Jiayu, Shukla, Rajni Kant, Liang, Xueya, Zou, Zhongyu, Cormet-Boyaka, Estelle, Qiu, Jianming, Peeples, Mark E., Sharma, Amit, He, Chuan, Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586267/
https://www.ncbi.nlm.nih.gov/pubmed/36240321
http://dx.doi.org/10.1073/pnas.2123338119

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