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Synaptic memory survives molecular turnover

Activation of Ca(2+)/calmodulin-dependent kinase II (CaMKII) plays a critical role in long-term potentiation (LTP), a long accepted cellular model for learning and memory. However, how LTP and memories survive the turnover of synaptic proteins, particularly CaMKII, remains a mystery. Here, we take a...

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Detalles Bibliográficos
Autores principales: Lee, Joel, Chen, Xiumin, Nicoll, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586278/
https://www.ncbi.nlm.nih.gov/pubmed/36215504
http://dx.doi.org/10.1073/pnas.2211572119