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Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat

The adaptor protein (AP) complexes not only form the inner layer of clathrin coats but also have clathrin-independent roles in membrane traffic whose mechanisms are unknown. HIV-1 Nef hijacks AP-1 to sequester major histocompatibility complex class I (MHC-I), evading immune detection. We found that...

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Detalles Bibliográficos
Autores principales: Hooy, Richard M., Iwamoto, Yuichiro, Tudorica, Dan A., Ren, Xuefeng, Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586487/
https://www.ncbi.nlm.nih.gov/pubmed/36269825
http://dx.doi.org/10.1126/sciadv.add3914