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A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention afte...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SMC Media Srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586506/ https://www.ncbi.nlm.nih.gov/pubmed/36299842 http://dx.doi.org/10.12890/2022_003553 |
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author | KC, Ojbindra Dahal, Punya Hari Koirala, Manisha Yadav, Sumeet Kumar |
author_facet | KC, Ojbindra Dahal, Punya Hari Koirala, Manisha Yadav, Sumeet Kumar |
author_sort | KC, Ojbindra |
collection | PubMed |
description | INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention after his second dose of the Pfizer COVID-19 vaccine. MRI of the spine revealed longitudinally extensive transverse myelitis (LETM). He recovered completely after treatment with intravenous methylprednisone and physical therapy. DISCUSSION: This case highlights the rare association between LETM and COVID-19 vaccines and encourages clinicians to maintain a high index of suspicion for prompt diagnosis and treatment. LEARNING POINTS: Longitudinally extensive transverse myelitis (LETM) is rare adverse events after mRNA COVID-19 vaccination. Clinicians should maintain a high index of suspicion for prompt diagnosis of vaccine-induced transverse myelitis. Vaccine-induced LETM should show marked clinical improvement after appropriate treatment. |
format | Online Article Text |
id | pubmed-9586506 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-95865062022-10-25 A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome KC, Ojbindra Dahal, Punya Hari Koirala, Manisha Yadav, Sumeet Kumar Eur J Case Rep Intern Med Article INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention after his second dose of the Pfizer COVID-19 vaccine. MRI of the spine revealed longitudinally extensive transverse myelitis (LETM). He recovered completely after treatment with intravenous methylprednisone and physical therapy. DISCUSSION: This case highlights the rare association between LETM and COVID-19 vaccines and encourages clinicians to maintain a high index of suspicion for prompt diagnosis and treatment. LEARNING POINTS: Longitudinally extensive transverse myelitis (LETM) is rare adverse events after mRNA COVID-19 vaccination. Clinicians should maintain a high index of suspicion for prompt diagnosis of vaccine-induced transverse myelitis. Vaccine-induced LETM should show marked clinical improvement after appropriate treatment. SMC Media Srl 2022-09-15 /pmc/articles/PMC9586506/ /pubmed/36299842 http://dx.doi.org/10.12890/2022_003553 Text en © EFIM 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Article KC, Ojbindra Dahal, Punya Hari Koirala, Manisha Yadav, Sumeet Kumar A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title | A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title_full | A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title_fullStr | A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title_full_unstemmed | A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title_short | A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome |
title_sort | rare case of longitudinally extensive transverse myelitis following pfizer-biontech covid-19 vaccination with a favourable outcome |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586506/ https://www.ncbi.nlm.nih.gov/pubmed/36299842 http://dx.doi.org/10.12890/2022_003553 |
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