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A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome

INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention afte...

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Autores principales: KC, Ojbindra, Dahal, Punya Hari, Koirala, Manisha, Yadav, Sumeet Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586506/
https://www.ncbi.nlm.nih.gov/pubmed/36299842
http://dx.doi.org/10.12890/2022_003553
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author KC, Ojbindra
Dahal, Punya Hari
Koirala, Manisha
Yadav, Sumeet Kumar
author_facet KC, Ojbindra
Dahal, Punya Hari
Koirala, Manisha
Yadav, Sumeet Kumar
author_sort KC, Ojbindra
collection PubMed
description INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention after his second dose of the Pfizer COVID-19 vaccine. MRI of the spine revealed longitudinally extensive transverse myelitis (LETM). He recovered completely after treatment with intravenous methylprednisone and physical therapy. DISCUSSION: This case highlights the rare association between LETM and COVID-19 vaccines and encourages clinicians to maintain a high index of suspicion for prompt diagnosis and treatment. LEARNING POINTS: Longitudinally extensive transverse myelitis (LETM) is rare adverse events after mRNA COVID-19 vaccination. Clinicians should maintain a high index of suspicion for prompt diagnosis of vaccine-induced transverse myelitis. Vaccine-induced LETM should show marked clinical improvement after appropriate treatment.
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spelling pubmed-95865062022-10-25 A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome KC, Ojbindra Dahal, Punya Hari Koirala, Manisha Yadav, Sumeet Kumar Eur J Case Rep Intern Med Article INTRODUCTION: mRNA COVID-19 vaccines are very safe, but rare adverse events such as transverse myelitis have been reported after COVID-19 vaccination. CASE DESCRIPTION: We report the case of 50-year-old man who presented with progressive lower extremity weakness, back pain and urinary retention after his second dose of the Pfizer COVID-19 vaccine. MRI of the spine revealed longitudinally extensive transverse myelitis (LETM). He recovered completely after treatment with intravenous methylprednisone and physical therapy. DISCUSSION: This case highlights the rare association between LETM and COVID-19 vaccines and encourages clinicians to maintain a high index of suspicion for prompt diagnosis and treatment. LEARNING POINTS: Longitudinally extensive transverse myelitis (LETM) is rare adverse events after mRNA COVID-19 vaccination. Clinicians should maintain a high index of suspicion for prompt diagnosis of vaccine-induced transverse myelitis. Vaccine-induced LETM should show marked clinical improvement after appropriate treatment. SMC Media Srl 2022-09-15 /pmc/articles/PMC9586506/ /pubmed/36299842 http://dx.doi.org/10.12890/2022_003553 Text en © EFIM 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Article
KC, Ojbindra
Dahal, Punya Hari
Koirala, Manisha
Yadav, Sumeet Kumar
A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title_full A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title_fullStr A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title_full_unstemmed A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title_short A Rare Case of Longitudinally Extensive Transverse Myelitis Following Pfizer-BioNTech COVID-19 Vaccination with a Favourable Outcome
title_sort rare case of longitudinally extensive transverse myelitis following pfizer-biontech covid-19 vaccination with a favourable outcome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586506/
https://www.ncbi.nlm.nih.gov/pubmed/36299842
http://dx.doi.org/10.12890/2022_003553
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