Targeting firing rate neuronal homeostasis can prevent seizures

Manipulating firing-rate neuronal homeostasis, which enables neurons to regulate their intrinsic excitability, offers an attractive opportunity to prevent seizures. However, to date, no drug-based interventions have been reported that manipulate this type of neuronal homeostatic mechanism. Here, we...

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Detalles Bibliográficos
Autores principales: Mulroe, Fred, Lin, Wei-Hsiang, Mackenzie-Gray Scott, Connie, Aourz, Najat, Fan, Yuen Ngan, Coutts, Graham, Parrish, R. Ryley, Smolders, Ilse, Trevelyan, Andrew, Wykes, Robert C., Allan, Stuart, Freeman, Sally, Baines, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586568/
https://www.ncbi.nlm.nih.gov/pubmed/36073607
http://dx.doi.org/10.1242/dmm.049703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586568/
https://www.ncbi.nlm.nih.gov/pubmed/36073607
http://dx.doi.org/10.1242/dmm.049703

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