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Targeting firing rate neuronal homeostasis can prevent seizures
Manipulating firing-rate neuronal homeostasis, which enables neurons to regulate their intrinsic excitability, offers an attractive opportunity to prevent seizures. However, to date, no drug-based interventions have been reported that manipulate this type of neuronal homeostatic mechanism. Here, we...
Autores principales: | Mulroe, Fred, Lin, Wei-Hsiang, Mackenzie-Gray Scott, Connie, Aourz, Najat, Fan, Yuen Ngan, Coutts, Graham, Parrish, R. Ryley, Smolders, Ilse, Trevelyan, Andrew, Wykes, Robert C., Allan, Stuart, Freeman, Sally, Baines, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586568/ https://www.ncbi.nlm.nih.gov/pubmed/36073607 http://dx.doi.org/10.1242/dmm.049703 |
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