Cargando…

Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system

Limited data exist on asthma and chronic obstructive pulmonary disease (COPD) management—major drivers of healthcare resource utilization (HCRU) in the USA. We describe prevalence and exacerbation rates, therapeutic interventions, and HCRU for asthma and/or COPD within a large, integrated healthcare...

Descripción completa

Detalles Bibliográficos
Autores principales: Collinsworth, Ashley W., Masica, Andrew L., Kudyakov, Rustam, Bayer, Valentina, Millard, Mark W., Shaikh, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586654/
https://www.ncbi.nlm.nih.gov/pubmed/36304620
http://dx.doi.org/10.1080/08998280.2022.2096370
_version_ 1784813731402743808
author Collinsworth, Ashley W.
Masica, Andrew L.
Kudyakov, Rustam
Bayer, Valentina
Millard, Mark W.
Shaikh, Asif
author_facet Collinsworth, Ashley W.
Masica, Andrew L.
Kudyakov, Rustam
Bayer, Valentina
Millard, Mark W.
Shaikh, Asif
author_sort Collinsworth, Ashley W.
collection PubMed
description Limited data exist on asthma and chronic obstructive pulmonary disease (COPD) management—major drivers of healthcare resource utilization (HCRU) in the USA. We describe prevalence and exacerbation rates, therapeutic interventions, and HCRU for asthma and/or COPD within a large, integrated healthcare system. Patients with asthma, COPD, and asthma + COPD were identified from retrospective electronic health record data (2016–2018) of >1.7 million patients. Descriptive analysis of disease prevalence and exacerbation frequencies, pharmacotherapies, and HCRU was performed. Time-to-event analysis of time to first exacerbation was performed in patients with asthma and/or COPD. Exacerbation rates, pharmacotherapies, and HCRU were examined by exploratory analysis in an outpatient subset. Overall, 149,086 unique patients (8.6%) had encounters for asthma, COPD, or asthma + COPD. Acute care utilization was high, including emergency department visits (asthma, 52.9%; COPD, 35.1%) and hospitalizations (asthma, 26.7%; COPD, 65.7%). Many patients were prescribed short-acting therapies (asthma, 45.3%; COPD, 40.0%; asthma + COPD, 54.7%). Prescription rates for maintenance therapies were low (17.1%, 20.8%, 31.7%) and annual exacerbation rates were 0.65, 0.80, and 1.33. This analysis showed a substantive prevalence of pulmonary disease, variability between documented prescriptions and pharmacotherapy guidelines, and high HCRU. Appropriate tailoring of pharmacotherapies and management of asthma and COPD over a continuum are opportunities to improve patient care.
format Online
Article
Text
id pubmed-9586654
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-95866542022-10-26 Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system Collinsworth, Ashley W. Masica, Andrew L. Kudyakov, Rustam Bayer, Valentina Millard, Mark W. Shaikh, Asif Proc (Bayl Univ Med Cent) Original Research Limited data exist on asthma and chronic obstructive pulmonary disease (COPD) management—major drivers of healthcare resource utilization (HCRU) in the USA. We describe prevalence and exacerbation rates, therapeutic interventions, and HCRU for asthma and/or COPD within a large, integrated healthcare system. Patients with asthma, COPD, and asthma + COPD were identified from retrospective electronic health record data (2016–2018) of >1.7 million patients. Descriptive analysis of disease prevalence and exacerbation frequencies, pharmacotherapies, and HCRU was performed. Time-to-event analysis of time to first exacerbation was performed in patients with asthma and/or COPD. Exacerbation rates, pharmacotherapies, and HCRU were examined by exploratory analysis in an outpatient subset. Overall, 149,086 unique patients (8.6%) had encounters for asthma, COPD, or asthma + COPD. Acute care utilization was high, including emergency department visits (asthma, 52.9%; COPD, 35.1%) and hospitalizations (asthma, 26.7%; COPD, 65.7%). Many patients were prescribed short-acting therapies (asthma, 45.3%; COPD, 40.0%; asthma + COPD, 54.7%). Prescription rates for maintenance therapies were low (17.1%, 20.8%, 31.7%) and annual exacerbation rates were 0.65, 0.80, and 1.33. This analysis showed a substantive prevalence of pulmonary disease, variability between documented prescriptions and pharmacotherapy guidelines, and high HCRU. Appropriate tailoring of pharmacotherapies and management of asthma and COPD over a continuum are opportunities to improve patient care. Taylor & Francis 2022-07-19 /pmc/articles/PMC9586654/ /pubmed/36304620 http://dx.doi.org/10.1080/08998280.2022.2096370 Text en Copyright © 2022 Baylor University Medical Center https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Original Research
Collinsworth, Ashley W.
Masica, Andrew L.
Kudyakov, Rustam
Bayer, Valentina
Millard, Mark W.
Shaikh, Asif
Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title_full Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title_fullStr Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title_full_unstemmed Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title_short Retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
title_sort retrospective observational study of asthma and chronic obstructive pulmonary disease prevalence and associated healthcare resource utilization in a large, integrated healthcare system
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586654/
https://www.ncbi.nlm.nih.gov/pubmed/36304620
http://dx.doi.org/10.1080/08998280.2022.2096370
work_keys_str_mv AT collinsworthashleyw retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem
AT masicaandrewl retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem
AT kudyakovrustam retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem
AT bayervalentina retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem
AT millardmarkw retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem
AT shaikhasif retrospectiveobservationalstudyofasthmaandchronicobstructivepulmonarydiseaseprevalenceandassociatedhealthcareresourceutilizationinalargeintegratedhealthcaresystem