Transcription Factor p300 Regulated miR-451b Weakens the Cigarette Smoke Extract-Induced Cellular Stress by Targeting RhoA/ROCK2 Signaling

BACKGROUND: A previous study identified miR-451b as a potential biomarker in smoker with or without chronic obstructive pulmonary disease (COPD). However, the function and molecular mechanisms of miR-451b in the pathogenesis of COPD remain elusive. METHODS: Macrophages and lung fibroblasts were expo...

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Detalles Bibliográficos
Autores principales: Shen, Wen, Wang, Shukun, Wang, Ruili, Zhang, Yang, Tian, Hong, Wang, Xi, Wu, Xin, Yang, Xiaolei, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586727/
https://www.ncbi.nlm.nih.gov/pubmed/36275894
http://dx.doi.org/10.1155/2022/7056283

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