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Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine

In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation tec...

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Autores principales: Sobahi, Nebras, Imran, Mohd, Khan, Mohammad Ehtisham, Mohammad, Akbar, Alam, Md. Mottahir, Yoon, Taeho, M. Mehedi, Ibrahim, Hussain, Mohammad A., Abdulaal, Mohammed J., A. Jiman, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586835/
https://www.ncbi.nlm.nih.gov/pubmed/36276988
http://dx.doi.org/10.1155/2022/6482133
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author Sobahi, Nebras
Imran, Mohd
Khan, Mohammad Ehtisham
Mohammad, Akbar
Alam, Md. Mottahir
Yoon, Taeho
M. Mehedi, Ibrahim
Hussain, Mohammad A.
Abdulaal, Mohammed J.
A. Jiman, Ahmad
author_facet Sobahi, Nebras
Imran, Mohd
Khan, Mohammad Ehtisham
Mohammad, Akbar
Alam, Md. Mottahir
Yoon, Taeho
M. Mehedi, Ibrahim
Hussain, Mohammad A.
Abdulaal, Mohammed J.
A. Jiman, Ahmad
author_sort Sobahi, Nebras
collection PubMed
description In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is I(pa) (μA) = 0.07701 c (μM) − 0.1232 (R(2) = 0.996), and the linear range is 5-75 μM. The limit of detection (LOD) and sensitivity were calculated as 0.868 μM and 421.1 μA/μM, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility.
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spelling pubmed-95868352022-10-22 Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine Sobahi, Nebras Imran, Mohd Khan, Mohammad Ehtisham Mohammad, Akbar Alam, Md. Mottahir Yoon, Taeho M. Mehedi, Ibrahim Hussain, Mohammad A. Abdulaal, Mohammed J. A. Jiman, Ahmad Bioinorg Chem Appl Research Article In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is I(pa) (μA) = 0.07701 c (μM) − 0.1232 (R(2) = 0.996), and the linear range is 5-75 μM. The limit of detection (LOD) and sensitivity were calculated as 0.868 μM and 421.1 μA/μM, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility. Hindawi 2022-10-14 /pmc/articles/PMC9586835/ /pubmed/36276988 http://dx.doi.org/10.1155/2022/6482133 Text en Copyright © 2022 Nebras Sobahi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sobahi, Nebras
Imran, Mohd
Khan, Mohammad Ehtisham
Mohammad, Akbar
Alam, Md. Mottahir
Yoon, Taeho
M. Mehedi, Ibrahim
Hussain, Mohammad A.
Abdulaal, Mohammed J.
A. Jiman, Ahmad
Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title_full Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title_fullStr Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title_full_unstemmed Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title_short Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
title_sort facile fabrication of cuo nanoparticles embedded in n-doped carbon nanostructure for electrochemical sensing of dopamine
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586835/
https://www.ncbi.nlm.nih.gov/pubmed/36276988
http://dx.doi.org/10.1155/2022/6482133
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