cfDNA methylome profiling for detection and subtyping of small cell lung cancers

Small cell lung cancer (SCLC) is characterized by morphologic, epigenetic and transcriptomic heterogeneity. Subtypes based upon predominant transcription factor expression have been defined that, in mouse models and cell lines, exhibit potential differential therapeutic vulnerabilities, with epigene...

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Detalles Bibliográficos
Autores principales: Chemi, Francesca, Pearce, Simon P., Clipson, Alexandra, Hill, Steven M., Conway, Alicia-Marie, Richardson, Sophie A., Kamieniecka, Katarzyna, Caeser, Rebecca, White, Daniel J., Mohan, Sumitra, Foy, Victoria, Simpson, Kathryn L., Galvin, Melanie, Frese, Kristopher K., Priest, Lynsey, Egger, Jacklynn, Kerr, Alastair, Massion, Pierre P., Poirier, John T., Brady, Gerard, Blackhall, Fiona, Rothwell, Dominic G., Rudin, Charles M., Dive, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586870/
https://www.ncbi.nlm.nih.gov/pubmed/35941262
http://dx.doi.org/10.1038/s43018-022-00415-9

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