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Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation

The parathyroid hormone type 1 receptor (PTH1R), a class B1 G protein-coupled receptor, plays critical roles in bone turnover and Ca(2+) homeostasis. Teriparatide (PTH) and Abaloparatide (ABL) are terms as long-acting and short-acting peptide, respectively, regarding their marked duration distinctio...

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Detalles Bibliográficos
Autores principales:	Zhai, Xiuwen, Mao, Chunyou, Shen, Qingya, Zang, Shaokun, Shen, Dan-Dan, Zhang, Huibing, Chen, Zhaohong, Wang, Gang, Zhang, Changming, Zhang, Yan, Liu, Zhihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586930/ https://www.ncbi.nlm.nih.gov/pubmed/36271004 http://dx.doi.org/10.1038/s41467-022-34009-x

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