Diverse maturity-dependent and complementary anti-apoptotic brakes safeguard human iPSC-derived neurons from cell death

In humans, most neurons are born during embryonic development and have to persist throughout the entire lifespan of an individual. Thus, human neurons have to develop elaborate survival strategies to protect against accidental cell death. We set out to decipher the developmental adaptations resultin...

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Detalles Bibliográficos
Autores principales: Wilkens, Ruven, Hoffrichter, Anne, Kleinsimlinghaus, Karolina, Bohl, Bettina, Haag, Carolin, Lehmann, Nadja, Schmidt, Malin, Muñoz Perez-Vico, Elena, Wangemann, Julia, Rehder, Klara Franziska, Horschitz, Sandra, Köhr, Georg, Ladewig, Julia, Koch, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587001/
https://www.ncbi.nlm.nih.gov/pubmed/36270985
http://dx.doi.org/10.1038/s41419-022-05340-4

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