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Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein

Amyloid aggregates of specific proteins constitute important pathological hallmarks in many neurodegenerative diseases, defining neuronal degeneration and disease onset. Recently, increasing numbers of patients show comorbidities and overlaps between multiple neurodegenerative diseases, presenting d...

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Detalles Bibliográficos
Autores principales:	Dhakal, Shailendra, Robang, Alicia S., Bhatt, Nemil, Puangmalai, Nicha, Fung, Leiana, Kayed, Rakez, Paravastu, Anant K., Rangachari, Vijayaraghavan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587012/ https://www.ncbi.nlm.nih.gov/pubmed/36116552 http://dx.doi.org/10.1016/j.jbc.2022.102498

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