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Generation and characterization of a Müller-glial-cell-specific Il6ra knockout mouse to delineate the effects of IL-6 trans-signaling in the retina

Interleukin-6 (IL-6) is implicated in various retinal and vascular complications associated with diabetic retinopathy (DR). This cytokine functions through two main modalities: classical signaling, in cells expressing the membrane-bound receptor (IL-6Rα); and trans-signaling, possible in most cells...

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Detalles Bibliográficos
Autores principales:	Robinson, Rebekah, Glass, Joshua, Sharma, Ashok, Sharma, Shruti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587029/ https://www.ncbi.nlm.nih.gov/pubmed/36271280 http://dx.doi.org/10.1038/s41598-022-22329-3

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