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Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography
Numerous studies have shown how periplasmic binding proteins (PBPs) bind substrates with exquisite specificity, even distinguishing between sugar epimers and anomers, or structurally similar ions. Yet, marked substrate promiscuity is also a feature encoded in some PBPs. Except for three sub-Ångström...
Autores principales: | Shukla, Shantanu, Myles, Dean A., Cuneo, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587032/ https://www.ncbi.nlm.nih.gov/pubmed/36271099 http://dx.doi.org/10.1038/s41598-022-20542-8 |
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