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Basement membrane defects in CD151-associated glomerular disease

BACKGROUND: CD151 is a cell-surface molecule of the tetraspanin family. Its lateral interaction with laminin-binding integrin ɑ3β1 is important for podocyte adhesion to the glomerular basement membrane (GBM). Deletion of Cd151 in mice induces glomerular dysfunction, with proteinuria and associated f...

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Detalles Bibliográficos
Autores principales: Naylor, Richard W., Watson, Elizabeth, Williamson, Samantha, Preston, Rebecca, Davenport, J Bernard, Thornton, Nicole, Lowe, Martin, Williams, Maggie, Lennon, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587066/
https://www.ncbi.nlm.nih.gov/pubmed/35278129
http://dx.doi.org/10.1007/s00467-022-05447-y

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