Optimization of whole-cell vaccines with CpG/αOX40/cGAMP to strengthen the anti-tumor response of CD4(+) T cells in melanomas

METHODS: In this study, we developed a strategy for the prevention and therapy of melanoma using a whole-cell vaccine combined with a CpG/αOX40/cGAMP triple adjuvant. The CpG/αOX40/cGAMP triple adjuvant was used to co-culture melanoma cells in vitro to induce immunogenic death of tumor cells. The mi...

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Detalles Bibliográficos
Autores principales: Du, Xuedan, Wu, Jinting, Zhao, Ye, Wang, Bin, Ding, Xiaobo, Lin, Qiuyan, Chen, Yingyu, Zhao, Jinduo, Liu, Lixiao, Mao, Xiaolu, Fang, Zhen, Zhang, Chunhong, Li, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587117/
https://www.ncbi.nlm.nih.gov/pubmed/35748951
http://dx.doi.org/10.1007/s00432-022-04117-8

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