Inhibitions and Down-Regulation of Motor Protein Eg5 Expression in Primary Sensory Neurons Reveal a Novel Therapeutic Target for Pathological Pain

The motor protein Eg5, known as kif11 or kinesin-5, interacts with adjacent microtubules in the mitotic spindle and plays essential roles in cell division, yet the function of Eg5 in mature postmitotic neurons remains largely unknown. In this study, we investigated the contribution and molecular mec...

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Detalles Bibliográficos
Autores principales: Wei, Na, Yu, Yang, Yang, Yan, Wang, Xiao-Liang, Zhong, Zhen-Juan, Chen, Xue-Feng, Yu, Yao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587155/
https://www.ncbi.nlm.nih.gov/pubmed/35764763
http://dx.doi.org/10.1007/s13311-022-01263-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587155/
https://www.ncbi.nlm.nih.gov/pubmed/35764763
http://dx.doi.org/10.1007/s13311-022-01263-2

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