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A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis

BACKGROUND: MicroRNAs are non-coding RNAs that negatively regulate gene networks. Previously, we reported that systemically delivered miR-29 mimic MRG-201 reduced fibrosis in animal models, supporting the consideration of miR-29-based therapies for idiopathic pulmonary fibrosis (IPF). METHODS: We ge...

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Detalles Bibliográficos
Autores principales:	Chioccioli, Maurizio, Roy, Subhadeep, Newell, Rachel, Pestano, Linda, Dickinson, Brent, Rigby, Kevin, Herazo-Maya, Jose, Jenkins, Gisli, Ian, Steward, Saini, Gauri, Johnson, Simon R., Braybrooke, Rebecca, Yu, Guying, Sauler, Maor, Ahangari, Farida, Ding, Shuizi, DeIuliis, Joseph, Aurelien, Nachelle, Montgomery, Rusty L., Kaminski, Naftali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587275/ https://www.ncbi.nlm.nih.gov/pubmed/36265417 http://dx.doi.org/10.1016/j.ebiom.2022.104304

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