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Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance

Chronic stress is associated with profound behavioral and physiological alterations, including intolerance to uncertainty and reduced resting-state heart-rate-variability (HRV). Critically, uncertainty may arise in situations with known probabilities (risk) or unknown probabilities (ambiguity). Whet...

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Autores principales: Jiryis, Talita, Magal, Noa, Fructher, Eyal, Hertz, Uri, Admon, Roee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587282/
https://www.ncbi.nlm.nih.gov/pubmed/36271286
http://dx.doi.org/10.1038/s41598-022-22584-4
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author Jiryis, Talita
Magal, Noa
Fructher, Eyal
Hertz, Uri
Admon, Roee
author_facet Jiryis, Talita
Magal, Noa
Fructher, Eyal
Hertz, Uri
Admon, Roee
author_sort Jiryis, Talita
collection PubMed
description Chronic stress is associated with profound behavioral and physiological alterations, including intolerance to uncertainty and reduced resting-state heart-rate-variability (HRV). Critically, uncertainty may arise in situations with known probabilities (risk) or unknown probabilities (ambiguity). Whether associations between chronic stress and decision-making under uncertainty are dependent on the specific type of uncertain decisions, and whether physiological alterations play a role in these putative associations is not yet clear. Here, ninety-two healthy adults that exhibit various levels of perceived chronic stress underwent resting-state HRV recording before completing a behavioral task that involves decision-making under either risk or ambiguity. Computational modelling quantified participants’ behavioral attitudes of approach and avoidance separately for risk and ambiguity. Results indicate, as expected, that perceived chronic stress is positively associated with intolerance to uncertainty and negatively associated with resting-state HRV. Contrary to expectations, behavioral attitudes towards risk and ambiguity were not directly associated with perceived chronic stress, yet HRV fully mediated the association between chronic stress and ambiguity avoidance. Taken together and given the direction of the associations, elevated HRV despite chronic stress may foster adaptive behavior in the form of avoiding ambiguous situations, and hence contribute to reduced exposure to uncertainty and to lower levels of allostatic load.
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spelling pubmed-95872822022-10-23 Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance Jiryis, Talita Magal, Noa Fructher, Eyal Hertz, Uri Admon, Roee Sci Rep Article Chronic stress is associated with profound behavioral and physiological alterations, including intolerance to uncertainty and reduced resting-state heart-rate-variability (HRV). Critically, uncertainty may arise in situations with known probabilities (risk) or unknown probabilities (ambiguity). Whether associations between chronic stress and decision-making under uncertainty are dependent on the specific type of uncertain decisions, and whether physiological alterations play a role in these putative associations is not yet clear. Here, ninety-two healthy adults that exhibit various levels of perceived chronic stress underwent resting-state HRV recording before completing a behavioral task that involves decision-making under either risk or ambiguity. Computational modelling quantified participants’ behavioral attitudes of approach and avoidance separately for risk and ambiguity. Results indicate, as expected, that perceived chronic stress is positively associated with intolerance to uncertainty and negatively associated with resting-state HRV. Contrary to expectations, behavioral attitudes towards risk and ambiguity were not directly associated with perceived chronic stress, yet HRV fully mediated the association between chronic stress and ambiguity avoidance. Taken together and given the direction of the associations, elevated HRV despite chronic stress may foster adaptive behavior in the form of avoiding ambiguous situations, and hence contribute to reduced exposure to uncertainty and to lower levels of allostatic load. Nature Publishing Group UK 2022-10-21 /pmc/articles/PMC9587282/ /pubmed/36271286 http://dx.doi.org/10.1038/s41598-022-22584-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Jiryis, Talita
Magal, Noa
Fructher, Eyal
Hertz, Uri
Admon, Roee
Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title_full Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title_fullStr Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title_full_unstemmed Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title_short Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
title_sort resting-state heart rate variability (hrv) mediates the association between perceived chronic stress and ambiguity avoidance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587282/
https://www.ncbi.nlm.nih.gov/pubmed/36271286
http://dx.doi.org/10.1038/s41598-022-22584-4
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