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HDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer

Histone deacetylase 6 (HDAC6), a member of the HDAC family, has been identified as a potential therapeutic target for tumor therapy, but the function and underlying mechanisms of HDAC6 in colon cancer are incompletely characterized. Our study showed that the infiltration ratio of M2 macrophages was...

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Detalles Bibliográficos
Autores principales:	Xu, Guangying, Niu, Liling, Wang, Youhui, Yang, Guang, Zhu, Xingwu, Yao, Yuan, Zhao, Gang, Wang, Shaowei, Li, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587286/ https://www.ncbi.nlm.nih.gov/pubmed/36270986 http://dx.doi.org/10.1038/s41419-022-05335-1

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