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Disease stages and therapeutic hypotheses in two decades of neurodegenerative disease clinical trials

Neurodegenerative disease is increasingly prevalent and remains without disease-modifying therapies. Engaging the right target, at the right disease stage, could be an important determinant of success. We annotated targets and eligibility criteria for 3238 neurodegenerative disease trials registered...

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Detalles Bibliográficos
Autores principales: Mortberg, Meredith A., Vallabh, Sonia M., Minikel, Eric Vallabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587287/
https://www.ncbi.nlm.nih.gov/pubmed/36271285
http://dx.doi.org/10.1038/s41598-022-21820-1