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Favine/CCDC3 deficiency accelerated atherosclerosis and thrombus formation is associated with decreased MEF2C-KLF2 pathway

Currently, no mouse models manifest calcification and thrombus formation, which is frequently associated with human atherosclerosis. We demonstrated that lack of Favine/CCDC3 in apoE knockout mice accelerated atherosclerosis accompanied by large cholesterol crystals and calcification, and also promo...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Sachiko, Kita, Shunbun, Okuzaki, Daisuke, Fujishima, Yuya, Otsuki, Michio, Kato, Hisashi, Nishizawa, Yasuko, Miyashita, Kazuya, Yokoyama, Chieko, Fukuhara, Atsunori, Morii, Eiichi, Shimomura, Iichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587315/ https://www.ncbi.nlm.nih.gov/pubmed/36281455 http://dx.doi.org/10.1016/j.isci.2022.105252

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