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Dopaminergic neurons are not a major Sonic hedgehog ligand source for striatal cholinergic or PV interneurons
A model was previously proposed that DA neurons provide SHH ligand to striatal interneurons, which in turn support the survival of DA neurons through the release of trophic factors such as Glial cell-derived neurotrophic factor (GDNF). However, some key clinical observations do not support this prop...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587326/ https://www.ncbi.nlm.nih.gov/pubmed/36281454 http://dx.doi.org/10.1016/j.isci.2022.105278 |