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Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage polarization and osteoclastogenesis

Extensive macrophage inflammatory responses and osteoclast formation are predominant during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small extracellular vesicles (MSC-sEV) have been shown to exert therapeutic effects on bone defects. However, cultured MSCs are typica...

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Detalles Bibliográficos
Autores principales:	Tian, Jun, Chen, Weiyang, Xiong, Yuhua, Li, Qianer, Kong, Siyi, Li, Mengjie, Pang, Chunfeng, Qiu, Yu, Xu, Zhezhen, Gong, Qimei, Wei, Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587346/ https://www.ncbi.nlm.nih.gov/pubmed/36311048 http://dx.doi.org/10.1016/j.bioactmat.2022.10.001

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