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Comparing biological effectiveness guided plan optimization strategies for cranial proton therapy: potential and challenges

BACKGROUND: To introduce and compare multiple biological effectiveness guided (BG) proton plan optimization strategies minimizing variable relative biological effectiveness (RBE) induced dose burden in organs at risk (OAR) while maintaining plan quality with a constant RBE. METHODS: Dose-optimized (...

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Detalles Bibliográficos
Autores principales:	Hahn, Christian, Heuchel, Lena, Ödén, Jakob, Traneus, Erik, Wulff, Jörg, Plaude, Sandija, Timmermann, Beate, Bäumer, Christian, Lühr, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587622/ https://www.ncbi.nlm.nih.gov/pubmed/36273132 http://dx.doi.org/10.1186/s13014-022-02143-x

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