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Chemical Replacement of Noggin with Dorsomorphin Homolog 1 for Cost-Effective Direct Neuronal Conversion

The direct conversion of adult human skin fibroblasts (FBs) into induced neurons (iNs) represents a useful technology to generate donor-specific adult-like human neurons. Disease modeling studies rely on the consistently efficient conversion of relatively large cohorts of FBs. Despite the identifica...

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Detalles Bibliográficos
Autores principales: Böhnke, Lena, Zhou-Yang, Lucia, Pelucchi, Silvia, Kogler, Flora, Frantal, Daniela, Schön, Florian, Lagerström, Stina, Borgogno, Oliver, Baltazar, Jennifer, Herdy, Joseph R., Kittel-Schneider, Sarah, Defrancesco, Michaela, Mertens, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587801/
https://www.ncbi.nlm.nih.gov/pubmed/35877103
http://dx.doi.org/10.1089/cell.2021.0200