Modern imaging in Cushing’s disease

Management of Cushing’s disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30–50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when...

Descripción completa

Detalles Bibliográficos
Autores principales: Bashari, W. A., Gillett, D., MacFarlane, J., Powlson, A. S., Kolias, A. G., Mannion, R., Scoffings, D. J., Mendichovszky, I. A., Jones, J., Cheow, H. K., Koulouri, O., Gurnell, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587975/
https://www.ncbi.nlm.nih.gov/pubmed/35666391
http://dx.doi.org/10.1007/s11102-022-01236-w
_version_ 1784814023565377536
author Bashari, W. A.
Gillett, D.
MacFarlane, J.
Powlson, A. S.
Kolias, A. G.
Mannion, R.
Scoffings, D. J.
Mendichovszky, I. A.
Jones, J.
Cheow, H. K.
Koulouri, O.
Gurnell, M.
author_facet Bashari, W. A.
Gillett, D.
MacFarlane, J.
Powlson, A. S.
Kolias, A. G.
Mannion, R.
Scoffings, D. J.
Mendichovszky, I. A.
Jones, J.
Cheow, H. K.
Koulouri, O.
Gurnell, M.
author_sort Bashari, W. A.
collection PubMed
description Management of Cushing’s disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30–50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when using standard clinical sequences. In this context, alternative MR protocols [e.g. 3D gradient (recalled) echo, with acquisition of volumetric data] may allow detection of tumors that have not been previously visualized. The use of hybrid molecular imaging (e.g. (11)C-methionine positron emission tomography coregistered with volumetric MRI) has also been proposed as an additional modality for localizing microadenomas.
format Online
Article
Text
id pubmed-9587975
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-95879752022-10-24 Modern imaging in Cushing’s disease Bashari, W. A. Gillett, D. MacFarlane, J. Powlson, A. S. Kolias, A. G. Mannion, R. Scoffings, D. J. Mendichovszky, I. A. Jones, J. Cheow, H. K. Koulouri, O. Gurnell, M. Pituitary Review Management of Cushing’s disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30–50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when using standard clinical sequences. In this context, alternative MR protocols [e.g. 3D gradient (recalled) echo, with acquisition of volumetric data] may allow detection of tumors that have not been previously visualized. The use of hybrid molecular imaging (e.g. (11)C-methionine positron emission tomography coregistered with volumetric MRI) has also been proposed as an additional modality for localizing microadenomas. Springer US 2022-06-06 2022 /pmc/articles/PMC9587975/ /pubmed/35666391 http://dx.doi.org/10.1007/s11102-022-01236-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Bashari, W. A.
Gillett, D.
MacFarlane, J.
Powlson, A. S.
Kolias, A. G.
Mannion, R.
Scoffings, D. J.
Mendichovszky, I. A.
Jones, J.
Cheow, H. K.
Koulouri, O.
Gurnell, M.
Modern imaging in Cushing’s disease
title Modern imaging in Cushing’s disease
title_full Modern imaging in Cushing’s disease
title_fullStr Modern imaging in Cushing’s disease
title_full_unstemmed Modern imaging in Cushing’s disease
title_short Modern imaging in Cushing’s disease
title_sort modern imaging in cushing’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587975/
https://www.ncbi.nlm.nih.gov/pubmed/35666391
http://dx.doi.org/10.1007/s11102-022-01236-w
work_keys_str_mv AT bashariwa modernimagingincushingsdisease
AT gillettd modernimagingincushingsdisease
AT macfarlanej modernimagingincushingsdisease
AT powlsonas modernimagingincushingsdisease
AT koliasag modernimagingincushingsdisease
AT mannionr modernimagingincushingsdisease
AT scoffingsdj modernimagingincushingsdisease
AT mendichovszkyia modernimagingincushingsdisease
AT jonesj modernimagingincushingsdisease
AT cheowhk modernimagingincushingsdisease
AT koulourio modernimagingincushingsdisease
AT gurnellm modernimagingincushingsdisease

Ejemplares similares