Longitudinal clinical and biomarker characteristics of non-manifesting LRRK2 G2019S carriers in the PPMI cohort

We examined 2-year longitudinal change in clinical features and biomarkers in LRRK2 non-manifesting carriers (NMCs) versus healthy controls (HCs) enrolled in the Parkinson’s Progression Markers Initiative (PPMI). We analyzed 2-year longitudinal data from 176 LRRK2 G2019S NMCs and 185 HCs. All partic...

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Detalles Bibliográficos
Autores principales: Simuni, Tanya, Merchant, Kalpana, Brumm, Michael C., Cho, Hyunkeun, Caspell-Garcia, Chelsea, Coffey, Christopher S., Chahine, Lana M., Alcalay, Roy N., Nudelman, Kelly, Foroud, Tatiana, Mollenhauer, Brit, Siderowf, Andrew, Tanner, Caroline, Iwaki, Hirotaka, Sherer, Todd, Marek, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588016/
https://www.ncbi.nlm.nih.gov/pubmed/36273008
http://dx.doi.org/10.1038/s41531-022-00404-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588016/
https://www.ncbi.nlm.nih.gov/pubmed/36273008
http://dx.doi.org/10.1038/s41531-022-00404-w

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