Characterization of somatic structural variations in 528 Chinese individuals with Esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) demonstrates high genome instability. Here, we analyze 528 whole genomes to investigate structural variations’ mechanisms and biological functions. SVs show multi-mode distributions in size, indicating distinct mutational processes. We develop a tool and def...

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Detalles Bibliográficos
Autores principales: Cui, Heyang, Zhou, Yong, Wang, Fang, Cheng, Caixia, Zhang, Weimin, Sun, Ruifang, Zhang, Ling, Bi, Yanghui, Guo, Min, Zhou, Yan, Wang, Xinhui, Ren, Jiaxin, Bai, Ruibing, Ding, Ning, Cheng, Chen, Wang, Longlong, Zhuang, Xuehan, Gao, Mingwei, Weng, Yongjia, Wu, Yueguang, Liu, Huijuan, Li, Shuaicheng, Wang, Shubin, Cheng, Xiaolong, Cui, Yongping, Liu, Zhihua, Zhan, Qimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588063/
https://www.ncbi.nlm.nih.gov/pubmed/36272974
http://dx.doi.org/10.1038/s41467-022-33994-3

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