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Chlormethine Gel for the Treatment of Mycosis Fungoides Cutaneous T-Cell Lymphoma: In Vitro Release and Permeation Testing

INTRODUCTION: The DNA-alkylating agent chlormethine (CL, or mechlorethamine) is approved in several countries worldwide as a 0.016% w/w topical CL gel formulation, to treat mycosis fungoides cutaneous T-cell lymphoma, with a positive benefit/risk ratio. METHODS: Release profiles of CL from the gel a...

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Detalles Bibliográficos
Autores principales:	Giuliano, Claudio, Frizzarin, Stefano, Alonzi, Alessandro, Stimamiglio, Virginia, Ortiz-Romero, Pablo L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Healthcare 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588113/ https://www.ncbi.nlm.nih.gov/pubmed/36229764 http://dx.doi.org/10.1007/s13555-022-00813-y

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